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| Reactivity: | Mouse |
| Applications: | FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal Antibody |
| Conjugation: | PE. Ex:565nm. Em:574nm. |
| Gene Name: | macrophage scavenger receptor 1 |
| Gene Symbol: | Msr1 |
| Synonyms: | MSR; SR-A; Scvr; MRS-A; MSR-A; SR-AI; SR-AII; Scara1 |
| Gene ID: | 20288 |
| UniProt ID: | P30204 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 350-458 of mouse CD204 (NP_001106797.1). |
| Dilution: | FC,5 μl per 10^6 cells in 100 μl volume |
| Purification Method: | Affinity purification |
| Concentration: | 0.04 mg/ml |
| Buffer: | PBS with 0.09% Sodium azide,0.2% BSA, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. |
| Documents: | Manual-Msr1 antibody |
Background
Enables amyloid-beta binding activity; cargo receptor activity; and low-density lipoprotein particle binding activity. Involved in several processes, including endocytosis; positive regulation of cholesterol storage; and positive regulation of macrophage derived foam cell differentiation. Acts upstream of or within establishment of localization in cell and lipoprotein transport. Located in plasma membrane. Is expressed in several structures, including alimentary system; early conceptus; limb; neural tube; and reproductive system. Human ortholog(s) of this gene implicated in Barrett's esophagus; arteriosclerosis; and prostate cancer. Orthologous to human MSR1 (macrophage scavenger receptor 1).
Images
 | Flow cytometry: 1×10^6 Neuro-2a cells (negative control,left) and RAW 264.7 cells (right) were surface-stained with PE Rabbit anti-Mouse CD204 mAb (A27278,5 μl/Test,orange line) or PE Rabbit IgG isotype control (A24172,5 μl/Test,blue line). Non-fluorescently stained cells were used as blank control (red line). |
 | Flow cytometry: 1×10^6 RAW 264.7 cells were surface-stained with PE Rabbit IgG isotype control (A24172,5 μl/Test,left) or PE Rabbit anti-Mouse CD204 mAb (A27278,5 μl/Test,right). |
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