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| Reactivity: | R |
| Applications: | IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | GAA1 rabbit polyclonal |
Gene Name: | Glycosylphosphatidylinositol anchor attachment 1 protein |
Synonyms: | GAA1, GAA1 protein homolog, GPAA1, hGAA1, GPI anchor attachment protein 1, mGAA1, Anchor attachment protein 1 (Gaa1p, yeast) homolog, GPI transamidase subunit |
Immunogen: | Recombinant protein corresponding to Mouse GAA1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Endoplasmic reticulum |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Rat | 1: 2000-1: 4000 | kidney |
Background
GPAA1(Glycosylphosphatidylinositol anchor attachment 1 protein) is also named as GAA1. It is the most conspicuously hydrophobic of the known subunits of GPIT, and it may play a key role in substrate recognition. It is predicted to be a multispanning membrane protein of 67 kDa with seven transmembrane (TM) domains, a large lumenal domain between the first two TM segments, and a cytoplasmically oriented N terminus bearing a potential ER retrieval signal in the form of a diarginine motif. It has 2 isoforms produced by alternative splicing and the full length protein has 2 glycosylation sites. This antibody is specific to GPAA1.
Images
 | Immunohistochemistry analysis of paraffin-embedded rat kidney using GAA1 (GB113592) at dilution of 1: 4000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |