| Reactivity: | M,R | 
| Applications: | IHC | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Full Name: | GADD45G/CR6 rabbit polyclonal  | 
Gene Name:  | Growth arrest and DNA damage-inducible protein GADD45 gamma  | 
Synonyms:  | Cytokine-responsive protein CR6, Gadd45g, Cr6, DDIT-2, DNA damage-inducible transcript 2 protein, GRP17  | 
Immunogen:  | Recombinant protein corresponding to Mouse GADD45G/CR6  | 
Isotype:  | IgG  | 
Purity:  | Affinity purification  | 
Subcellular location:  | Nucleus, Cytoplasm  | 
Uniprot ID:  | 
Product Usage Information
Applications  | Species  | Dilution  | Positive tissue  | 
IHC  | Mouse, Rat  | 1: 2000-1: 4000  | cerebellum  | 
Background
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta.
Images
  | Immunohistochemistry analysis of paraffin-embedded mouse cerebellum using GADD45G (GB113573) at dilution of 1: 4000  | 
  | Immunohistochemistry analysis of paraffin-embedded rat cerebellum using GADD45G (GB113573) at dilution of 1: 4000  | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |