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Anti-GSDMD Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Gasdermin-D |
Synonyms: | DF5L, DFNA5L, FKSG10, gasdermin D, GSDMD, GSDMDC1 |
Immunogen: | Recombinant protein corresponding to Human GSDMD |
Uniprot ID: | P57764 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 53 kDa / 53 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1:500- 1：1000 | lung, liver |
Background
GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
Images
| Western blot analysis of GSDMD (GB114198) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |