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| Reactivity: | Human |
| Applications: | WB, ELISA |
| Host Species: | Rabbit |
| Clonality: | Polyclonal antibody |
| Gene Name: | HEAT repeat containing 1 |
| Gene Symbol: | HEATR1 |
| Synonyms: | BAP28; UTP10; HEATR1 |
| Gene ID: | 55127 |
| UniProt ID: | Q9H583 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human HEATR1 (NP_060542.4). |
| Dilution: | WB 1:500-1:2000 |
| Purification Method: | Affinity purification |
| Concentration: | 2.02 mg/ml |
| Buffer: | PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
| Documents: | Manual-HEATR1 antibody |
Background
Enables RNA binding activity. Involved in positive regulation of rRNA processing and positive regulation of transcription by RNA polymerase I. Located in fibrillar center and mitochondrion. Implicated in pancreatic ductal carcinoma. Biomarker of glioblastoma.
Images
 | Western blot analysis of lysates from HeLa cells, using HEATR1 Rabbit pAb (A13102) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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