| Reactivity: | H,M,R | 
| Applications: | WB | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Gene Name: | Huntingtin-interacting protein 1-related protein  | 
Synonyms:  | HIP 12, HIP1 related protein, HIP12, HIP1R, HIP3, ILWEQ, KIAA0655  | 
Immunogen:  | KLH conjugated Synthetic peptide corresponding to Mouse HIP1R  | 
Uniprot ID:  | Q9JKY5  | 
Isotype:  | IgG  | 
Purity:  | Affinity purification  | 
Predicted MW. / Observed MW.  | 119 kDa / 115 kDa  | 
Product Usage Information
WB  | Human, Mouse, Rat  | 1: 2000-1: 4000  | placenta, liver, heart, brain  | 
Background
Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.
Images
  | Western blot analysis of HIP1R (GB114275) at dilution of 1: 2000  | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |