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Anti-HMGA1 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | HMGA1 rabbit polyclonal |
Gene Name: | High mobility group protein HMG-I/HMG-Y |
Synonyms: | High mobility group AT-hook protein 1, High mobility group protein A1, HMG-I(Y), Hmgi, Hmgiy, Hmga1, Nonhistone chromosomal high mobility group protein HMG I/HMG Y |
Immunogen: | Recombinant protein corresponding to Mouse HMGA1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human | 1: 700-1: 1400 | colon cancer, stomach |
Background
HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions.
Images
| Immunohistochemistry analysis of paraffin-embedded human colon cancer using HMGA1 (GB113561) at dilution of 1: 1400 |
| Immunohistochemistry analysis of paraffin-embedded human stomach using HMGA1 (GB113561) at dilution of 1: 1400 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |