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Anti-HMGCL Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Hydroxymethylglutaryl-CoA lyase, mitochondrial |
Synonyms: | HL, HMG CoA lyase, HMGCL |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse HMGCL |
Uniprot ID: | P38060 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 34 kDa / 30 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 3000-1: 5000 | liver, kidney |
Background
Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.
Images
| Western blot analysis of HMGCL (GB114264) at dilution of 1: 3000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |