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| Reactivity: | Human, Mouse |
| Applications: | WB, IHC, ELISA |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal antibody |
| Gene Name: | hyaluronan mediated motility receptor |
| Gene Symbol: | HMMR |
| Synonyms: | CD168; IHABP; RHAMM; CD168/RHAMM |
| Gene ID: | 3161 |
| UniProt ID: | O75330 |
| Clone ID: | 3L10H9 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CD168/RHAMM (O75330). |
| Dilution: | WB 1:100-1:500; IHC 1:50-1:200 |
| Purification Method: | Affinity purification |
| Concentration: | 1.95 mg/ml |
| Buffer: | PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
| Documents: | Manual-HMMR antibody |
Background
The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Images
 | Western blot analysis of lysates from K-562 cells, using CD168/RHAMM Rabbit mAb (A11666) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 180s. |
 | Immunohistochemistry analysis of paraffin-embedded Mouse kidney using CD168/RHAMM Rabbit mAb (A11666) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining. |
 | Immunohistochemistry analysis of paraffin-embedded Human esophageal using CD168/RHAMM Rabbit mAb (A11666) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining. |
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