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Anti-HSD3B7 Rabbit pAb (100 μl)
| Reactivity: | H,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | HSD3B7 rabbit polyclonal |
Gene Name: | 3 beta-hydroxysteroid dehydrogenase type 7 |
Synonyms: | 3 beta-hydroxysteroid dehydrogenase type VII, 3-beta-HSD VII, C(27) 3-beta-HSD, Hsd3b7, SDR11E3, PFIC4 |
Immunogen: | Recombinant protein corresponding to Mouse HSD3B7 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 41 kDa |
Observed MW. | 45 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Rat | 1: 500-1: 1000 | HeLa |
Background
This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Images
 | Western blot analysis of HSD3B7 (GB112714) at dilution of 1: 1000 Lane 1: HeLa cell lysate |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |