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| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | IB-2 rabbit polyclonal |
Gene Name: | C-Jun-amino-terminal kinase-interacting protein 2 |
Synonyms: | JNK-interacting protein 2, JIP-2, Islet-brain-2, IB-2, JNK MAP kinase scaffold protein 2, Mitogen-activated protein kinase 8-interacting protein 2, Mapk8ip2, Ib2, Jip2 |
Immunogen: | Recombinantproteincorrespondingto Mouse IB-2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 90kDa |
Observed MW. | 100kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 300-1: 1000 | lung |
Background
The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP2 inhibits IL1 beta-induced apoptosis in insulin-secreting cells. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins.
Images
| Western blot analysis of IB-2 (GB113539) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |