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Anti-IFNL3 Rabbit pAb (100 μl)
| Reactivity: | R & R |
| Applications: | IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | IFNL3 rabbit polyclonal |
Gene Name: | Interferon lambda-3 |
Synonyms: | IFN-lambda-3, Interleukin-28B, IL-28B, Ifnl3, Il28, Il28b |
Immunogen: | Recombinant protein corresponding to Mouse IFNL3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Rat | 1: 1000-1: 2000 | testis |
IF | Rat | 1: 200-1: 400 | skin |
Background
This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
Images
 | Immunohistochemistry analysis of paraffin-embedded rat testis using IFNL3 (GB112711) at dilution of 1: 2000 |
| Immunofluorescent analysis of paraformaldehyde-fixed rat skin using IFNL3 (GB112711) at dilution of 1: 400 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |