| Reactivity: | H,M,R | 
| Applications: | WB | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Full Name: | IL-17RA Receptor rabbit polyclonal antibody  | 
Gene Name:  | Interleukin-17 receptor A  | 
Synonyms:  | IL17RA, CANDF5, CD217, CDw217, IL-17RA, IL17R, hIL-17R, interleukin 17 receptor A, IMD51  | 
Immunogen:  | KLH conjugated Synthetic peptide corresponding to Mouse IL17RA  | 
Isotype:  | IgG  | 
Purity:  | Affinity purification  | 
Predicted MW.  | 96 kDa  | 
Observed MW.  | 96 kDa  | 
Uniprot ID:  | Q96F46, Q60943  | 
Product Usage Information
Applications  | Species  | Dilution  | Positive Sample  | 
WB  | Human, Mouse, Rat  | 1: 500-1: 1000  | lung, colon  | 
Background
Receptor for IL17A . Receptor for IL17F. Binds to IL17A with higher affinity than to IL17F . Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC . Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC . Receptor for IL17C as part of a heterodimeric complex with IL17RE . Activation of IL17RA leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1, CXCL8/IL8 and IL6.
Images
  | 
 Western blot analysis of IL-17R (GB11289) at dilution of 1: 500  | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. | 
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |