| Reactivity: | H,M,R & H,M | 
| Applications: | WB & IHC/IF | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Full Name: | IL-18R Beta/IL-18RAP rabbit polyclonal antibody  | 
Gene Name:  | Interleukin-18 receptor accessory protein  | 
Synonyms:  | IL18RAP, Accessory protein like, AcPL, CD218 antigen-like family member B, CD218b, CDw218b, IL-1R7, IL18R Beta, IL18RAP, Interleukin-18 receptor beta chain  | 
Immunogen:  | Recombinant protein corresponding to Mouse IL-18R Beta/IL-18RAP  | 
Isotype:  | IgG  | 
Purity:  | Affinity purification  | 
Predicted MW.  | 70 kDa  | 
Observed MW.  | 70 kDa  | 
Uniprot ID:  | Q9Z2B1  | 
Product Usage Information
Applications  | Species  | Dilution  | Positive Sample  | 
WB  | Human, Mouse, Rat  | 1: 1000-1: 4000  | lung, kidney, brain  | 
IHC/IF  | Human, Mouse  | 1: 1000-1: 4000  | spleen  | 
Background
Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation . May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (By similarity).
Images
  | Western blot analysis of CD218b (GB114098) at dilution of 1: 1000  | 
  | Immunohistochemistry analysis of paraffin embedded human spleen using CD218b (GB114098) at dilution of 1: 2000  | 
  | Immunohistochemistry analysis of paraffin embedded mouse spleen using CD218b (GB114098) at dilution of 1: 2000  | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |