Your shopping cart is empty!
| Reactivity: | Human |
| Applications: | WB, FC |
| Host Species: | Mouse |
| Isotype: | IgG2a |
| Clonality: | Monoclonal antibody |
| Gene Name: | aladin WD repeat nucleoporin |
| Gene Symbol: | AAAS |
| Synonyms: | AAA; AAASb; GL003; ALADIN; ADRACALA; ADRACALIN |
| Gene ID: | 8086 |
| UniProt ID: | Q9NRG9 |
| Clone ID: | 24GB8035 |
| Immunogen: | Recombinant protein of human AAAS |
| Dilution: | WB 1:1,000-1:5,000; FC 1:1,000 |
| Purification Method: | Affinity purified |
| Concentration: | Lot dependent |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
Background
The protein encoded by this gene is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene.
Images
 | Western blotting analysis using anti-aladin WD repeat nucleoporin antibody (Cat#63820). Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-aladin WD repeat nucleoporin antibody (Cat#63820, 1:5,000) and HRP-conjugated goat anti-mouse secondary antibody (Cat#101, 1:20,000) respectively. Image was developed using FeQ™ ECL Substrate Kit (Cat#226). |
 | Western blotting analysis using anti-aladin WD repeat nucleoporin antibody (Cat#63820). Aladin WD repeat nucleoporin expression in wild type (WT) and aladin WD repeat nucleoporin (AAAS) shRNA knockdown (KD) HeLa cells with 20 μg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with anti-aladin WD repeat nucleoporin antibody (Cat#63820, 1:5,000) and HRP-conjugated goat anti-mouse secondary antibody (Cat#101, 1:20,000) respectively. Image was developed using NaQ™ ECL Substrate Kit (Cat#716). |
 | Flow cytometric analysis of Aladin WD repeat nucleoporin expression in HAP-1 cells using anti-Aladin WD repeat nucleoporin antibody (Cat#63820, 1:1,000). Green, isotype control; red, Aladin WD repeat nucleoporin. |
You may also be interested in:
