Your shopping cart is empty!
| Reactivity: | Human, Rat |
| Applications: | WB |
| Host Species: | Mouse |
| Isotype: | IgG1 |
| Clonality: | Monoclonal antibody |
| Gene Name: | aldehyde dehydrogenase 4 family member A1 |
| Gene Symbol: | ALDH4A1 |
| Synonyms: | P5CD; ALDH4; P5CDh |
| Gene ID: | 8659 |
| UniProt ID: | P30038 |
| Clone ID: | 25GB525 |
| Immunogen: | Recombinant protein of human ALDH4A1 |
| Dilution: | WB 1:1,000-1:2,500 |
| Purification Method: | Affinity purified |
| Concentration: | Lot dependent |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
Background
This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Images
 | Western blotting analysis using anti-ALDH4A1 antibody (Cat#61263). Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-ALDH4A1 antibody (Cat#61263, 1:2,500) and HRP-conjugated goat anti-mouse secondary antibody (Cat#101, 1:20,000) respectively. Image was developed using FeQ™ ECL Substrate Kit (Cat#226). |
 | Western blotting analysis using anti-ALDH4A1 antibody (Cat#61263). ALDH4A1 expression in wild-type (WT) and ALDH4A1 shRNA knockdown (KD) HeLa cells with 30 μg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with anti-ALDH4A1 antibody (Cat#61263, 1:1,000) and HRP-conjugated goat anti-mouse secondary antibody (Cat#101, 1:20,000) respectively. Image was developed using FeQ™ ECL Substrate Kit (Cat#226). |
You may also be interested in:
