Your shopping cart is empty!
| Reactivity: | Human |
| Applications: | WB, FC |
| Host Species: | Mouse |
| Isotype: | IgG1 |
| Clonality: | Monoclonal antibody |
| Gene Name: | cytokine receptor like factor 3 |
| Gene Symbol: | CRLF3 |
| Synonyms: | FRWS; CRLM9; p48.2; CREME9; CYTOR4; CREME-9 |
| Gene ID: | 51379 |
| UniProt ID: | Q8IUI8 |
| Clone ID: | 24GB8640 |
| Immunogen: | Recombinant protein of human CRLF3 |
| Dilution: | WB 1:200-1:1,000; FC 1:2,000 |
| Purification Method: | Affinity purified |
| Concentration: | Lot dependent |
| Buffer: | PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
Background
This gene encodes a cytokine receptor-like factor that may negatively regulate cell cycle progression at the G0/G1 phase. Studies of the related rat protein suggest that it may regulate neuronal morphology and synaptic vesicle biogenesis. This gene is one of several genes located in the neurofibromatosis type I tumor suppressor region on the q arm of chromosome 17, a region that is subject to microdeletions, duplications, chromosomal breaks and rearrangements. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2 and 5.
Images
 | Western blotting analysis using anti-cytokine receptor like factor 3 antibody (Cat#63834). Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-cytokine receptor like factor 3 antibody (Cat#63834, 1:1,000) and HRP-conjugated goat anti-mouse secondary antibody (Cat#101, 1:20,000) respectively. Image was developed using NaQ™ ECL Substrate Kit (Cat#716). |
 | Western blotting analysis using anti-cytokine receptor like factor 3 antibody (Cat#63834). Cytokine receptor like factor 3 expression in wild-type (WT) and cytokine receptor like factor 3 (CRLF3) shRNA knockdown (KD) HeLa cells with 20 μg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with anti-cytokine receptor like factor 3 antibody (Cat#63834, 1:1,000) and HRP-conjugated goat anti-mouse secondary antibody (Cat#101, 1:20,000) respectively. Image was developed using FeQ™ ECL Substrate Kit (Cat#226). |
 | Flow cytometric analysis of Cytokine receptor like factor 3 expression in HepG2 cells using anti-Cytokine receptor like factor 3 antibody (Cat#63834, 1:2,000). Green, isotype control; red, Cytokine receptor like factor 3. |
You may also be interested in:
