KD-Validated GRHPR Mouse mAb (20 μl)

KD-Validated GRHPR Mouse mAb (20 μl)

Cat. #: 63508
Availability: In Stock
$149.00
-+
Reactivity:   Human    
Applications:   WB    
Host Species:   Mouse    
Isotype:   IgG2a    
Clonality:   Monoclonal antibody    
Gene Name:   glyoxylate and hydroxypyruvate reductase
Gene Symbol:   GRHPR
Synonyms:   PH2; GLXR; GLYD
Gene ID:   9380
UniProt ID:   Q9UBQ7
Clone ID:   24GB6270
Immunogen:   Recombinant protein of human GRHPR
Dilution:   WB 1:2,500-1:5,000
Purification Method:   Affinity purified
Concentration:   Lot dependent
Buffer:   PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Storage:   Store at -20°C. Avoid freeze/thaw cycles.




Background

This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene.




Images

GRHPR antibodyWestern blotting analysis using anti-GRHPR antibody (Cat#63508). Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-GRHPR antibody (Cat#63508, 1:5,000) and HRP-conjugated goat anti-mouse secondary antibody (Cat#101, 1:20,000) respectively. Image was developed using FeQ™ ECL Substrate Kit (Cat#226).
Western blotting analysis using anti-GRHPR antibody (Cat#63508). GRHPR expression in wild type (WT) and GRHPR shRNA knockdown (KD) HeLa cells with 20 μg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with anti-GRHPR antibody (Cat#63508, 1:5,000) and HRP-conjugated goat anti-mouse secondary antibody (Cat#101, 1:20,000) respectively. Image was developed using anti-FeQ™ ECL Substrate Kit (Cat#226).



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