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| Reactivity: | Human |
| Applications: | WB, FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal antibody |
| Gene Name: | p53 apoptosis effector related to PMP22 |
| Gene Symbol: | PERP |
| Synonyms: | THW; KCP1; EKVP7; OLMS2; PIGPC1; KRTCAP1; dJ496H19.1 |
| Gene ID: | 64065 |
| UniProt ID: | Q96FX8 |
| Clone ID: | 24GB1630 |
| Immunogen: | A synthesized peptide derived from human PERP |
| Dilution: | WB 1:1,000-1:5,000; FC 1:2,000 |
| Purification Method: | Affinity purified |
| Concentration: | Lot dependent |
| Buffer: | PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
Background
Involved in activation of cysteine-type endopeptidase activity and positive regulation of neutrophil chemotaxis. Predicted to be located in desmosome and plasma membrane. Predicted to be active in cell-cell junction. Implicated in erythrokeratodermia variabilis and mutilating palmoplantar keratoderma with periorificial keratotic plaques.
Images
 | Western blotting analysis using anti-PERP antibody (Cat#62608). Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-PERP antibody (Cat#62608, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (Cat#201, 1:20,000) respectively. Image was developed using FeQ™ ECL Substrate Kit (Cat#226). |
 | Western blotting analysis using anti-PERP antibody (Cat#62608). PERP expression in wild type (WT) and PERP shRNA knockdown (KD) HeLa cells with 20 μg of total cell lysates . β-Tubulin serves as a loading control. The blot was incubated with anti-PERP antibody (Cat#62608, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (Cat#201, 1:20,000) respectively. Image was developed using NaQ™ ECL Substrate Kit (Cat#716). |
 | Flow cytometric analysis of PERP expression in Hela cells using anti-PERP antibody (Cat#62608, 1:2,000). Green, isotype control; red, PERP. |
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