Your shopping cart is empty!
| Reactivity: | Human, Mouse, Rat |
| Applications: | WB, FC, IC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal antibody |
| Gene Name: | matrin 3 |
| Gene Symbol: | MATR3 |
| Synonyms: | MPD2; ALS21; VCPDM |
| Gene ID: | 9782 |
| UniProt ID: | P43243 |
| Clone ID: | 24GB535 |
| Immunogen: | A synthesized peptide derived from human Matrin 3 |
| Dilution: | WB 1:1,000-1:5,000; FC 1:2,000; IC 1:100-1:1,000 |
| Purification Method: | Affinity purified |
| Concentration: | Lot dependent |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
Background
This gene encodes a nuclear matrix protein, which is proposed to stabilize certain messenger RNA species. Mutations of this gene are associated with distal myopathy 2, which often includes vocal cord and pharyngeal weakness. Alternatively spliced transcript variants, including read-through transcripts composed of the upstream small nucleolar RNA host gene 4 (non-protein coding) and matrin 3 gene sequence, have been identified. Pseudogenes of this gene are located on chromosomes 1 and X.
Images
 | Western blotting analysis using anti-Matrin 3 antibody (Cat#62374). Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-Matrin 3 antibody (Cat#62374, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (Cat#201, 1:20,000) respectively. Image was developed using FeQ™ ECL Substrate Kit (Cat#226). |
 | Western blotting analysis using anti-Matrin 3 antibody (Cat#62374). Matrin 3 expression in wild type (WT) and Matrin 3 shRNA knockdown (KD) HeLa cells with 20 μg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with anti-Matrin 3 antibody (Cat#62374, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (Cat#201, 1:20,000) respectively. Image was developed using Plus ECL Super Kit (Cat#636). |
 | Flow cytometric analysis of Matrin 3 expression in HAP-1 cells using anti-Matrin 3 antibody (Cat#62374, 1:2,000). Green, isotype control; red, Matrin 3. |
 | Immunocytochemical staining of HAP-1 cells with anti-Matrin 3 antibody (Cat#62374, 1:1,000). Nuclei were stained blue with DAPI; Matrin 3 was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm. |
You may also be interested in:
