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| Reactivity: | Human, Mouse, Rat |
| Applications: | WB, FC |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal antibody |
| Gene Name: | transcription factor Dp-1 |
| Gene Symbol: | TFDP1 |
| Synonyms: | DP1; DILC; Dp-1; DRTF1 |
| Gene ID: | 7027 |
| UniProt ID: | Q14186 |
| Clone ID: | 24GB2685 |
| Immunogen: | A synthesized peptide derived from human DP1 |
| Dilution: | WB 1:1,000-1:5,000; FC 1:2,000 |
| Purification Method: | Affinity purified |
| Concentration: | Lot dependent |
| Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
Background
This gene encodes a member of a family of transcription factors that heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. The encoded protein functions as part of this complex to control the transcriptional activity of numerous genes involved in cell cycle progression from G1 to S phase. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1, 15, and X.
Images
 | Western blotting analysis using anti-transcription factor Dp-1 antibody (Cat#62819). Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-transcription factor Dp-1 antibody (Cat#62819, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (Cat#201, 1:20,000) respectively. Image was developed using FeQ™ ECL Substrate Kit (Cat#226). |
 | Western blotting analysis using anti-transcription factor Dp-1 antibody (Cat#62819). Transcription factor Dp-1 expression in wild-type (WT) and transcription factor Dp-1 (TFDP1) shRNA knockdown (KD) HeLa cells with 30 μg of total cell lysates . Hsp90 α serves as a loading control. The blot was incubated with anti-transcription factor Dp-1 antibody (Cat#62819, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (Cat#201, 1:20,000) respectively. Image was developed using NaQ™ ECL Substrate Kit (Cat#716). |
 | Flow cytometric analysis of transcription factor Dp-1 expression in C2C12 cells using anti-transcription factor Dp-1 antibody (Cat#62819, 1:2,000). Green, isotype control; red, transcription factor Dp-1. |
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