| Reactivity: | H,M,R | 
| Applications: | IHC/IF | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Full Name: | KHDRBS3 rabbit polyclonal antibody  | 
Gene Name:  | KH domain-containing, RNA-binding, signal transduction-associated protein 3  | 
Synonyms:  | Etle, etoile, KHDRBS3, RNA binding protein T Star, SALP, Sam68 like mammalian protein 2, SLM 2, SLM2, T STAR, TSTAR  | 
Immunogen:  | Recombinant protein corresponding to Mouse KHDRBS3  | 
Isotype:  | IgG  | 
Purity:  | Affinity purification  | 
Subcellular location:  | Nucleus  | 
Uniprot ID:  | Q9R226  | 
Product Usage Information
Applications  | Species  | Dilution  | Positive Sample  | 
IHC/IF  | Human, Mouse, Rat  | 1: 500-1: 1000  | kidney, brain  | 
Background
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Binds preferentially to the 5'-[AU]UAAA-3' motif in vitro . Binds optimally to RNA containing 5'-[AU]UAA-3' as a bipartite motif spaced by more than 15 nucleotides (By similarity). Binds poly(A). RNA-binding abilities are down-regulated by tyrosine kinase PTK6 . Involved in splice site selection of vascular endothelial growth factor (By similarity).
Images
  | Immunohistochemistry analysis of paraffin embedded human kidney using KHDRBS3 (GB114103) at dilution of 1: 500  | 
  | Immunohistochemistry analysis of paraffin embedded mouse brain using KHDRBS3 (GB114103) at dilution of 1: 500  | 
  | Immunohistochemistry analysis of paraffin embedded rat brain using KHDRBS3 (GB114103) at dilution of 1: 500  | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |