Cytokeratin 2e (KRT2) Rabbit pAb (20 μl)

Cytokeratin 2e (KRT2) Rabbit pAb (20 μl)

Brand: Abclonal
Cat. #: A10375
Availability: In Stock
$108.00
-+
Reactivity: Human, Mouse, Rat    
Applications: WB, ELISA    
Host Species: Rabbit    
Isotype: IgG    
Clonality: Polyclonal antibody    
Gene Name: keratin 2
Gene Symbol: KRT2
Synonyms: K2e; KRTE; CK-2e; KRT2A; KRT2E; Cytokeratin 2e (KRT2)
Gene ID: 3849
UniProt ID: P35908
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human Cytokeratin 2e (KRT2) (NP_000414.2).
Dilution: WB 1:500-1:2000
Purification Method: Affinity purification
Concentration: 4.3 mg/ml
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Documents: Manual-KRT2 antibody




Background

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.




Images

KRT2 antibodyWestern blot analysis of various lysates using Cytokeratin 2e (KRT2) Rabbit pAb (A10375) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 90s.



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