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| Product Category: | Mouse lentivirus expressing Aurka |
| Description: | Premade lentivirus for over-expression of mouse Aurka and control, ready to use format. |
| Gene Name: | aurora kinase A |
| Gene Symbol: | Aurka |
| Synonyms: | IAK; Ark1; Ayk1; IAK1; Stk6; AIRK1; ARK-1; Aurora-A |
| ACCN: | NM_011497.5 |
| Gene ID: | 20878 |
| Vector: | pLVX-Puro |
| Fusion Tag: | 3×Flag |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
Enables histone H3S10 kinase activity and ubiquitin protein ligase binding activity. Acts upstream of or within several processes, including microtubule cytoskeleton organization; positive regulation of oocyte maturation; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Located in axon hillock; microtubule cytoskeleton; and nucleus. Is active in glutamatergic synapse and postsynaptic density. Is expressed in several structures, including alimentary system; bone; brain; eye; and genitourinary system. Human ortholog(s) of this gene implicated in colorectal cancer; ovarian cancer; and uterine cancer. Orthologous to human AURKA (aurora kinase A).
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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