Product Category: | Human lentivirus expressing CBX3 |
Description: | Premade lentivirus for over-expression of human CBX3 and control, ready to use format. |
Gene Name: | chromobox 3 |
Gene Symbol: | CBX3 |
Synonyms: | HECH; HP1gamma; HP1-GAMMA; HP1Hs-gamma |
Gene ID: | 11335 |
Vector: | PDS407_pL-CMV-RFP-ccdB-puro |
Promoter: | CMV |
Titer: | ≥1E+8TU/ml |
Buffer: | PBS |
Storage: | -80°C |
Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.
Optional Services
Name | Catalog # | Turnaround Time | View |
Gene Synthesis | S0012 | Quote | ![]() |
Lentivirus Packaging | S0032 | Quote | ![]() |
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