| Product Category: | Human lentivirus expressing CEACAM5 |
| Description: | Premade lentivirus for over-expression of human CEACAM5 and control, ready to use format. |
| Gene Name: | CEA cell adhesion molecule 5 |
| Gene Symbol: | CEACAM5 |
| Synonyms: | CEA; CD66e |
| Gene ID: | 1048 |
| Vector: | pCDH-CMV-MCS-EF1-copGFP-T2A-Puro |
| Fusion Tag: | 3×Flag |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
The gene CEACAM5 encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote | |
| Lentivirus Packaging | S0032 | Quote |
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