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| Product Category: | Rat lentivirus expressing Fto |
| Description: | Premade lentivirus for over-expression of rat Fto and control, ready to use format. |
| Gene Name: | FTO, alpha-ketoglutarate dependent dioxygenase |
| Gene Symbol: | Fto |
| Synonyms: | RGD1305121 |
| ACCN: | NM_001039713.1 |
| Gene ID: | 291905 |
| Vector: | VP098-EF1a-MCS |
| Promoter: | EF1a |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
Predicted to enable 2-oxoglutarate-dependent dioxygenase activity and ferrous iron binding activity. Involved in several processes, including negative regulation of eating behavior; positive regulation of insulin secretion involved in cellular response to glucose stimulus; and response to bisphenol A. Predicted to be located in cytosol; nuclear speck; and plasma membrane. Used to study sciatic neuropathy. Biomarker of metabolic dysfunction-associated steatotic liver disease; obesity; transient cerebral ischemia; traumatic brain injury; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); diabetic neuropathy; nuclear senile cataract; renal cell carcinoma (multiple); and type 2 diabetes mellitus. Orthologous to human FTO (FTO alpha-ketoglutarate dependent dioxygenase).
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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