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| Product Category: | Human lentivirus expressing GSDME |
| Description: | Premade lentivirus for over-expression of human GSDME and control, ready to use format. |
| Gene Name: | gasdermin E |
| Gene Symbol: | GSDME |
| Synonyms: | DFNA5; ICERE-1 |
| ACCN: | NM_004403.3 |
| Gene ID: | 1687 |
| Vector: | VP001-CMV-MCS-EF1-ZsGreen-T2A-PURO |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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