Your shopping cart is empty!
| Product Category: | Human lentivirus expressing HOTAIR |
| Description: | Premade lentivirus for over-expression of human HOTAIR and control, ready to use format. |
| Gene Name: | HOX transcript antisense RNA |
| Gene Symbol: | HOTAIR |
| Synonyms: | HOXAS; HOXC-AS4; HOXC11-AS1; NCRNA00072 |
| ACCN: | NR_003716.4 |
| Gene ID: | 100124700 |
| Vector: | pLVX-Puro |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene is located within the Homeobox C (HOXC) gene cluster on chromosome 12 and is co-expressed with the HOXC genes. It functions through an RNA product, which binds lysine specific demethylase 1 (LSD1) and Polycomb repressive complex 2 (PRC2), and serves as a scaffold to assemble these regulators at the HOXD gene cluster, thereby promoting epigenetic repression of HOXD. This gene is highly expressed in multiple tumors. Alternatively spliced transcript variants have been identified.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
You may also be interested in:
