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| Product Category: | Human lentivirus expressing ITGA5 |
| Description: | Premade lentivirus for over-expression of human ITGA5 and control, ready to use format. |
| Gene Name: | Integrin subunit alpha 5 |
| Gene Symbol: | ITGA5 |
| Synonyms: | FNRA; CD49e; VLA-5; VLA5A |
| ACCN: | NM_002205.5 |
| Gene ID: | 3678 |
| Vector: | VP-CMV-MCS-3×Flag-EF1-ZsGreen-T2A-PURO |
| Fusion Tag: | Flag |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
The product of the gene ITGA5 belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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