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| Product Category: | Mouse lentivirus expressing Kdm6a |
| Description: | Premade lentivirus for over-expression of mouse Kdm6a and control, ready to use format. |
| Gene Name: | lysine (K)-specific demethylase 6A |
| Gene Symbol: | Kdm6a |
| Synonyms: | Utx |
| ACCN: | NM_001310444.2 |
| Gene ID: | 22289 |
| Vector: | pCDH-PURO |
| Fusion Tag: | HA |
| Promoter: | CMV |
| Mutation: | G2080A |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
Enables DNA binding activity; histone H3K27me2/H3K27me3 demethylase activity; and identical protein binding activity. Involved in chromatin remodeling. Acts upstream of or within several processes, including chordate embryonic development; embryonic morphogenesis; and respiratory system process. Located in nucleus. Part of histone methyltransferase complex. Is expressed in several structures, including alimentary system; early conceptus; gonad; liver; and spleen. Used to study chronic myelomonocytic leukemia. Human ortholog(s) of this gene implicated in several diseases, including Kabuki syndrome; bladder urothelial carcinoma; gastrointestinal system cancer (multiple); lung carcinoma (multiple); and triple-receptor negative breast cancer. Orthologous to human KDM6A (lysine demethylase 6A).
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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