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| Product Category: | Human lentivirus expressing LEFTY1 |
| Description: | Premade lentivirus for over-expression of human LEFTY1 and control, ready to use format. |
| Gene Name: | left-right determination factor 1 |
| Gene Symbol: | LEFTY1 |
| Synonyms: | LEFTB; LEFTYB |
| ACCN: | NM_020997.4 |
| Gene ID: | 10637 |
| Vector: | VP001-CMV-MCS-EF1-ZsGreen-T2A-PURO |
| Fusion Tag: | Flag |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. This gene is closely linked to both a related family member and a related pseudogene.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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