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| Product Category: | Human lentivirus expressing LMX1B |
| Description: | Premade lentivirus for over-expression of human LMX1B and control, ready to use format. |
| Gene Name: | LIM homeobox transcription factor 1 beta |
| Gene Symbol: | LMX1B |
| Synonyms: | NPS1; FSGS10; LMX1.2 |
| ACCN: | NM_001174147 |
| Gene ID: | 4010 |
| Vector: | PCDH-hPGK-MCS-EF1-copGFP-T2A-Puro |
| Fusion Tag: | Myc |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene encodes a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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