Lentivirus MAT1A (5×200 μl)

Lentivirus MAT1A (5×200 μl)

Cat. #: M2181
Availability: In Stock
$699.00
-+
Product Category: Human lentivirus expressing MAT1A    
Description: Premade lentivirus for over-expression of human MAT1A and control, ready to use format.
Gene Name: methionine adenosyltransferase 1A
Gene Symbol: MAT1A
Synonyms: MAT; SAMS; MATA1; SAMS1
ACCN: NM_00429.3
Gene ID: 4143
Vector: pCDH-EF1-MCS-CMV-copGFP-T2A-Puro
Promoter: EF1
Selection Antibiotic: Puromycin
Titer: ≥1E+8TU/ml
Buffer: PBS
Storage: -80°C
Documents: Manual-Ready-to-Use Recombinant Lentivirus



Background

This gene catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency.



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