| Product Category: | Human lentivirus expressing MFGE8 |
| Description: | Premade lentivirus for over-expression of human MFGE8 and control, ready to use format. |
| Gene Name: | milk fat globule EGF and factor V/VIII domain containing |
| Gene Symbol: | MFGE8 |
| Synonyms: | BA46; HMFG; MFGM; SED1; hP47; EDIL1; MFG-E8; SPAG10; OAcGD3S; HsT19888 |
| Gene ID: | 4240 |
| Vector: | VP007-CMV-MCS-EF1-puro |
| Fusion Tag: | Flag, EGFP |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote | |
| Lentivirus Packaging | S0032 | Quote |
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