| Product Category: | Human lentivirus expressing NCBP2 |
| Description: | Premade lentivirus for over-expression of human NCBP2 and control, ready to use format. |
| Gene Name: | nuclear cap binding protein subunit 2 |
| Gene Symbol: | NCBP2 |
| Synonyms: | CBC2; NIP1; CBP20; PIG55 |
| ACCN: | NM_007362.5 |
| Gene ID: | 22916 |
| Vector: | VP004-CMV-MCS-3×Flag-EF1-fLUC-T2A-PURO |
| Fusion Tag: | Flag |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been found for this gene.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote | |
| Lentivirus Packaging | S0032 | Quote |
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