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| Product Category: | Human lentivirus expressing NSUN2 |
| Description: | Premade lentivirus for over-expression of human NSUN2 and control, ready to use format. |
| Gene Name: | NOP2/Sun RNA methyltransferase 2 |
| Gene Symbol: | NSUN2 |
| Synonyms: | MISU; MRT5; SAKI; TRM4 |
| ACCN: | NM_001193455.2 |
| Gene ID: | 54888 |
| Vector: | PCDH-3×Flag-NSUN2-EGFP-Puro |
| Fusion Tag: | Flag |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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