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| Product Category: | Human lentivirus expressing PIK3CA |
| Description: | Premade lentivirus for over-expression of human PIK3CA and control, ready to use format. |
| Gene Name: | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
| Gene Symbol: | PIK3CA |
| Synonyms: | HMH; MCM; CCM4; CWS5; MCAP; PI3K; CLAPO; CLOVE; MCMTC; PI3K-alpha; p110-alpha |
| ACCN: | NM_006218.4 |
| Gene ID: | 5290 |
| Vector: | VP007-CMV-MCS-3×Flag-EF1-puro |
| Promoter: | CMV |
| Mutation: | H1047R |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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