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| Product Category: | Mouse lentivirus expressing Pak1 |
| Description: | Premade lentivirus for over-expression of mouse Pak1 and control, ready to use format. |
| Gene Name: | p21 (RAC1) activated kinase 1 |
| Gene Symbol: | Pak1 |
| Synonyms: | Paka; PAK-1 |
| ACCN: | NM_011035.3 |
| Gene ID: | 18479 |
| Vector: | VP001-CMV-MCS-3×Flag-EF1-ZsGreen-T2A-PURO |
| Fusion Tag: | 3×Flag |
| Promoter: | CMV |
| Mutation: | P212A |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
Enables protein serine/threonine kinase activity. Involved in regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission. Acts upstream of or within several processes, including nervous system development; neurotransmitter secretion; and observational learning. Located in several cellular components, including dendrite; growth cone; and nucleus. Is active in GABA-ergic synapse; glutamatergic synapse; and postsynaptic density. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in breast cancer; renal cell carcinoma; and schizophrenia. Orthologous to human PAK1 (p21 (RAC1) activated kinase 1).
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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