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| Product Category: | Mouse lentivirus expressing Rac2 |
| Description: | Premade lentivirus for over-expression of mouse Rac2 and control, ready to use format. |
| Gene Name: | Rac family small GTPase 2 |
| Gene Symbol: | Rac2 |
| ACCN: | NM_009008.3 |
| Gene ID: | 19354 |
| Vector: | pLVX-mCherry-C1 (puro) |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
Enables GTPase activity and protein kinase regulator activity. Involved in several processes, including positive regulation of lamellipodium assembly; regulation of leukocyte chemotaxis; and regulation of mast cell degranulation. Acts upstream of or within several processes, including cell projection assembly; erythrocyte enucleation; and positive regulation of mast cell proliferation. Located in cytoplasm; membrane; and nuclear envelope. Is expressed in heart; maxilla; palatal shelf; and secondary palate. Used to study immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia. Human ortholog(s) of this gene implicated in immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosis; immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia; and immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemia. Orthologous to human RAC2 (Rac family small GTPase 2).
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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