Your shopping cart is empty!
| Product Category: | Human lentivirus expressing SARS2 |
| Description: | Premade lentivirus for over-expression of human SARS2 and control, ready to use format. |
| Gene Name: | seryl-tRNA synthetase 2, mitochondrial |
| Gene Symbol: | SARS2 |
| Synonyms: | SYS; SARS; SERS; SARSM; SerRS; SerRSmt; mtSerRS |
| Gene ID: | 54938 |
| Vector: | pLenti EF1a-SARS2 N-Flag-BSD |
| Promoter: | EF1a |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a bidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease. Multiple transcript variants encoding different isoforms have been identified for this gene.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
You may also be interested in:
