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| Product Category: | Human lentivirus expressing TLK1 |
| Description: | Premade lentivirus for over-expression of human TLK1 and control, ready to use format. |
| Gene Name: | tousled like kinase 1 |
| Gene Symbol: | TLK1 |
| Synonyms: | PKU-beta |
| ACCN: | NM_001136554.2 |
| Gene ID: | 9874 |
| Vector: | VP004-CMV-MCS-3×Flag-EF1-fLUC-T2A-PURO |
| Fusion Tag: | Flag |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
The protein encoded by this gene is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The encoded protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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