Lentivirus TRIM27 (5×200 μl)

Lentivirus TRIM27 (5×200 μl)

Cat. #: M2260
Availability: In Stock
$699.00
-+
Product Category: Human lentivirus expressing TRIM27    
Description: Premade lentivirus for over-expression of human TRIM27 and control, ready to use format.
Gene Name: tripartite motif containing 27
Gene Symbol: TRIM27
Synonyms: RFP; RNF76
ACCN: NM_006510.5
Gene ID: 5987
Vector: VP001-CMV-MCS-EF1-ZsGreen-T2A-PURO
Fusion Tag: 3×HA
Promoter: CMV
Selection Antibiotic: Puromycin
Titer: ≥1E+8TU/ml
Buffer: PBS
Storage: -80°C
Documents: Manual-Ready-to-Use Recombinant Lentivirus



Background

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein.



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