Lentivirus TSHR (5×200 μl)

Lentivirus TSHR (5×200 μl)

Cat. #: M2319
Availability: In Stock
$699.00
-+
Product Category: Human lentivirus expressing TSHR    
Description: Premade lentivirus for over-expression of human TSHR and control, ready to use format.
Gene Name: Thyroid stimulating hormone receptor
Gene Symbol: TSHR
Synonyms: LGR3; CHNG1; hTSHR-I
ACCN: NM_000369.5
Gene ID: 7253
Vector: pLVX-Puro
Promoter: CMV
Selection Antibiotic: Puromycin
Titer: ≥1E+8TU/ml
Buffer: PBS
Storage: -80°C
Documents: Manual-Ready-to-Use Recombinant Lentivirus



Background

The protein encoded by the gene TSHR is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.



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