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| Product Category: | Mouse lentivirus expressing Tyrobp |
| Description: | Premade lentivirus for over-expression of mouse Tyrobp and control, ready to use format. |
| Gene Name: | TYRO protein tyrosine kinase binding protein |
| Gene Symbol: | Tyrobp |
| Synonyms: | Ly83; DAP12; KARAP |
| ACCN: | NM_011662.3 |
| Gene ID: | 22177 |
| Vector: | VP007-CMV-MCS-EF1-puro |
| Promoter: | CMV |
| Selection Antibiotic: | Blasticidin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
Enables signaling receptor binding activity. Involved in several processes, including myeloid cell activation involved in immune response; regulation of cytokine production; and regulation of lymphocyte activation. Acts upstream of or within osteoclast differentiation and regulation of osteoclast development. Located in cell surface. Is expressed in blood vessel; brain; central nervous system; corpus callosum; and embryo. Used to study Nasu-Hakola disease. Human ortholog(s) of this gene implicated in Nasu-Hakola disease. Orthologous to human TYROBP (transmembrane immune signaling adaptor TYROBP).
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote |  |
| Lentivirus Packaging | S0032 | Quote | |
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