| Product Category: | Human lentivirus expressing VPREB1 |
| Description: | Premade lentivirus for over-expression of human VPREB1 and control, ready to use format. |
| Gene Name: | V-set pre-B cell surrogate light chain 1 |
| Gene Symbol: | VPREB1 |
| Synonyms: | IGI; IGVPB; VPREB; CD179a |
| ACCN: | NM_007128.4 |
| Gene ID: | 7441 |
| Vector: | pLVX-Puro |
| Fusion Tag: | 3×Flag |
| Promoter: | CMV |
| Selection Antibiotic: | Puromycin |
| Titer: | ≥1E+8TU/ml |
| Buffer: | PBS |
| Storage: | -80°C |
| Documents: | Manual-Ready-to-Use Recombinant Lentivirus |
Background
The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. Alternative splicing results in multiple transcript variants.
Optional Services
| Name | Catalog # | Turnaround Time | View |
| Gene Synthesis | S0012 | Quote | |
| Lentivirus Packaging | S0032 | Quote |
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