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| Reactivity: | Human, Mouse, Rat |
| Applications: | WB, ELISA |
| Host Species: | Rabbit |
| Clonality: | Polyclonal antibody |
| Gene Name: | MARVEL domain containing 2 |
| Gene Symbol: | MARVELD2 |
| Synonyms: | Tric; DFNB49; MARVD2; MRVLDC2; MARVELD2 |
| Gene ID: | 153562 |
| UniProt ID: | Q8N4S9 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human MARVELD2 (NP_001033692.2). |
| Dilution: | WB 1:500-1:2000 |
| Purification Method: | Affinity purification |
| Concentration: | 1.00 mg/ml |
| Buffer: | PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
| Documents: | Manual-MARVELD2 antibody |
Background
The protein encoded by this gene is a membrane protein found at the tight junctions between epithelial cells. The encoded protein helps establish epithelial barriers such as those in the organ of Corti, where these barriers are required for normal hearing. Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49). Two transcript variants encoding different isoforms have been found for this gene.
Images
 | Western blot analysis of various lysates using MARVELD2 Rabbit pAb (A12612) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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