| Reactivity: | H,M,R | 
| Applications: | WB | 
| Host Species: | Rabbit | 
| Clonality: | Polyclonal | 
| Full Name: | MED6 rabbit polyclonal antibody  | 
Gene Name:  | Mediator of RNA polymerase II transcription subunit 6  | 
Synonyms:  | ARC33, hMed6, MED6, mediator complex subunit 6, NY REN 28  | 
Immunogen:  | Recombinant protein corresponding to Mouse MED6  | 
Isotype:  | IgG  | 
Purity:  | Affinity purification  | 
Predicted MW.  | 28 kDa  | 
Observed MW.  | 35 kDa  | 
Uniprot ID:  | Q921D4  | 
Product Usage Information
Applications  | Species  | Dilution  | Positive Sample  | 
WB  | Human, Mouse, Rat  | 1: 300-1: 1000  | lung  | 
Background
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Images
  | Western blot analysis of MED6 (GB114088) at dilution of 1: 1000  | 
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. | 
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |