Your shopping cart is empty!
| Reactivity: | Human, Mouse, Rat |
| Applications: | IF/IC, ELISA |
| Host Species: | Rabbit |
| Isotype: | IgG |
| Clonality: | Monoclonal antibody |
| Gene Name: | melanocyte inducing transcription factor |
| Gene Symbol: | MITF |
| Synonyms: | MI; WS2; CMM8; WS2A; COMMAD; MITF-A; bHLHe32; MITF |
| Gene ID: | 4286 |
| UniProt ID: | O75030 |
| Clone ID: | 9P1O1 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 387-509 of human MITF (O75030). |
| Dilution: | IF/IC 1:50-1:200 |
| Purification Method: | Affinity purification |
| Concentration: | 0.8 mg/mL |
| Buffer: | PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Storage: | Store at -20°C. Avoid freeze/thaw cycles. |
| Documents: | Manual-MITF antibody |
Background
The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome.
Images
 | Confocal imaging of HeLa cells using MITF Rabbit mAb (A11649,dilution 1:100)(Red). The cells were counterstained with α-Tubulin Mouse mAb (AC012,dilution 1:400) (Green). DAPI was used for nuclear staining (blue). Objective: 60x. |
You may also be interested in:
