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Anti-NHERF-2/SIP-1 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | NHERF-2/SIP-1 rabbit polyclonal antibody |
Gene Name: | Na(+)/H(+) exchange regulatory cofactor NHE-RF2 |
Synonyms: | NHERF-2, NHE3 kinase A regulatory protein E3KARP, Octs2, SRY-interacting protein 1, SIP-1, TKA-1, Slc9a3r2, Nherf2 |
Immunogen: | Recombinant protein corresponding to Mouse NHERF-2/SIP-1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 37 kDa |
Observed MW. | 37 kDa |
Uniprot ID: | Q9JHL1, Q920G2 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 2000 | brain, kidney, colon |
Background
This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Images
 | Western blot analysis of NHERF-2 (GB112708) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |